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The pyrimidine ring of your inhibitor overlies the adenine foundation. The bulky pyrido substituent with the inhibitor that fills the tunnel is undoubtedly an offshoot with the equivalent in the adenine C-2 (denoted with the black arrows
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Pues bien, a la par de esta noticia hay otra buena que tiene que ver ya más con el tema de los abonos y las boletas para este semestre.
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). The NTase area binds towards the broken and intact DNA strands in the foremost groove flanking the nick as well as from the slight groove within the three′-OH side in the nick (supplemental Fig. S3). The OB area binds throughout the minor groove over the deal with of your duplex at the rear of the nick.
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